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The mechanisms of INK4-ARF inactivation

   
@article{ARH3685,
	author = {Minggang Fang},
	title = {The mechanisms of INK4-ARF inactivation},
	journal = {Annals of Research Hospitals},
	volume = {1},
	number = {2},
	year = {2017},
	keywords = {},
	abstract = {Inactivation of the INK4-ARF locus is one of the most frequent events in cancers. The mechanistic basis of epigenetic silencing was not well understood. Recently Gamell et al. found a novel mechanism, in which loss of an E3 ubiquitin ligase E6AP results in the silencing of INK4-ARF locus through E2F-CDC6 pathway.},
	issn = {2523-0743},	url = {https://arh.amegroups.org/article/view/3685}
}